Get familiar with frequently used knowledge bases

• OncoKB: An FDA-recognized precision oncology knowledge base
• Cancer Hotspots: A resource of recurrent mutational hotspots in cancer
• 3D Hotspots: A resource of recurrent mutational cancer hotspots in 3D protein structures​
• Mutation Signatures: COSMIC Mutational Signatures is a catalogue of curated reference mutational signatures
• COSMIC: the Catalogue Of Somatic Mutations In Cancer, is the world’s largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer.
• cBioPortal: A leading resource for cancer genomics research. MSKCC’s instance https://cbioportal.mskcc.org
• Genome Nexus: A resource for comprehensive variant annotation​
• SignalDB: A resource that integrates germline and somatic alterations identified by in the MSK-IMPACT clinical sequencing cohort
• OncoTree: A cancer classification system for precision oncology